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Stress axis regulation DSIP acts as what researchers call a "stress-limiting factor." It modulates the hypothalamic-pituitary-adrenal (HPA) axis, the hormonal cascade responsible for your body's stress response

The consequences of phosphorylation and eventual hyperphosphorylation of Tau can lead to the loss of its normal homeostatic functions and is increasingly cytotoxicity (Liu et al., 2020)