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At present, it is generally believed that the simpler anesthetics used, the shorter time, and the fewer anesthetic times could alleviate the neurotoxicity of intravenous anesthetics, and the damage to neurological function after general anesthesia due to individual neurological susceptibility needs to be further confirmed

Voltage-gated ion channels that open or close in response to changes in the membrane potential

Specifically, expression of the gene ICOS was significantly negatively correlated with E2F6 expression, whereas U87 cell growth was reduced upon E2F6 knockout through short hairpin RNA (shRNA) [139]