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PubMed, doi:10.1159/000490071

Samantha has a degree in Journalism and Mass Communications from The George Washington Universitys School of Media and Public Affairs

Free radicals, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are a product of aerobic metabolism

While a marked increase in tumor volume was observed in the control group by day 15, no significant tumor enlargement was detected in the group treated with Spirulina polysaccharides ( In the hepatocellular carcinoma (HCC) model, Spirulina has been observed to increase survival and significantly reduce AFP levels, a tumor marker, as well as the number and volume of hepatic nodules

These findings suggest that TLR4 and RAGE signaling may contribute to distinct stages of dAGEs-induced allergic inflammation: TLR4 drives early barrier disruption and localized inflammation, while RAGE is essential for later-stage immune cell activation and allergen-specific responses

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