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Rationale-based engineering of a potent long-acting FGF21 analog for the treatment of type 2 diabetes

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These tests involved progressively increasing the workload, starting at 60 watts with a 15-W increment every minute, continuing until participants reached their physical limits

Calpain activity is increased in skeletal muscle from gastric cancer patients with no or minimal weight loss

It is worth mentioning that aberrantly increased levels of NO, RNS, and NO-related PTMs, including SNO, can also significantly affect autophagosomal biogenesis