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360 LPA plays a central role in this cascade by promoting HSC proliferation, survival, and the transition of HSCs to ECM-secreting myofibroblasts

Adenosine attenuates oxidant injury in human proximal tubular cells via A 1 and A 2a adenosine receptors

In previously published protocols different types of derivatization reagents (CMQT or CMLT), different pH of the buffer used in the protocols (7.4) and shorter time of sample reduction and derivatization (3 min) were applied (Tables 3 and 4.) Changing the conditions of reduction and derivatization increases the efficiency of this process, which may give higher final concentrations of the analytes

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Collectively, these mechanisms all indicate a reduced and more balanced stress response