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For instance, the depletion of GSH, a major cellular antioxidant that is essential for detoxifying ROS and maintaining redox balance within the cell (Akhigbe and Ajayi 2020

Gut 66, 429437

In contrast, another trial in 409 women with breast cancer found that ALCAR (3 g/day for 24 weeks) increased anticancer drug (taxanes)-induced peripheral neuropathy and decreased measures of functional status compared to placebo (91)