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Quelle: Sacco, Rodolfo, Roberto Eggenhoffner, and Luca Giacomelli

Over time, not getting enough B12 can lead to anaemia (low red blood cells), and in more serious cases, it can cause neurological problems like difficulty walking, numbness, or even memory loss

In animal models, it upregulates the anti-apoptotic protein Bcl-2, downregulates the pro-apoptotic protein Bax, alters mitochondrial membrane permeability, and inhibits the activation of executioner caspases such as caspase-3, thereby blocking the apoptotic signaling pathway (Liang et al., 2015)

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The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice

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