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McBride, J

PMID: 38232801, PMCID: PMC10932879, DOI: 10.1016/j.metabol.2024.155792

Titrate the dosage of hydrocodone bitartrate and acetaminophen tablets slowly in geriatric patients and frequently reevaluate the patient for signs of central nervous system and respiratory depression [see WARNINGS]

It goes to your brain and it hits your hypothalamic pituitary axis and it starts shutting down your hormones

For single timepoint permeabilization experiments, values were normalized to measurements obtained under 0 M Ca 2+ and osmotic-balanced (2.5% PVP) conditions

Protein expression was induced by 1 mmol l 1 isopropyl--thiogalactopyranoside for 4 h at 37 C