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Valproate-induced hyperammonaemic encephalopathy In chronic VPA dosing hyperammonaemia occurs in nearly 50% of patients, but this remains asymptomatic in almost 50% of cases [39]

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TMAO gilt als eine Substanz, die Arteriosklerose frdert, und erhhte TMAO-Spiegel korrelieren mit einem erhhten Risiko fr Herz-Kreislauf-Erkrankungen und Insulinresistenz