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PMID 26175657

P., DOrazio L

Nitrate/nitrite was analyzed using commercially available assay kits (Caymen Chemical, Ann Arbor, MI)

Since FAD is reported to be more easily dislodged from the structure of the MTHFR 677TT coded enzyme in its thermo-labile, low-activity form (105), one evolutionary benefit of this homozygous polymorphism may be its provision of dislodged un-utilized FAD for sustaining MAO enzyme activity and keeping vitamin B6 and D activated

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