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2a), indicating that LBNP-PC@M promotes the proliferation of vascular endothelial cells without exhibiting cytotoxicity toward trophoblast cells

for instance, it activates the TLR4/NF-B/miR-21 axis to downregulate RASA1 and drive tumor growth (Yang et al., 2017), and its adhesin RadD binds to CD147 to activate the PI3K-AKT-NF-B-MMP9 pathway (Wang et al., 2024) and confers resistance to 5-fluorouracil by upregulating BIRC3 through TLR4/NF-B signaling (Zhang et al., 2019)

Circ Cardiovasc Interv

Expert Opinion on Therapeutic Targets, 23 (7), 555558

Dickinson SE, Janda J, Criswell J, Blohm-Mangone K, Olson ER, Liu Z, et al

10.1038/jcbfm.2015.115 J