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To further confirm the effects of synaptic activity on the intrinsic GSH system, we performed an experiment employing Grx1-roGFP2, which reports in real time the glutathione redox potential through its coupling to redox-sensitive GFP via its fusion to glutaredoxin 26

The highest activity in this model demonstrated CD34 positive elements with earliest peak at 4th day, followed by VEGF (peak at 14th day) and FVIII (peak at 21 day)

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