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The severity of dengue infection varies widely, suggesting immune pathological, genetic and viral type factors may play a role in disease severity [6] [7] [8] [9]

Pediatr Nephrol 25:24592467

and disrupted synthesis and release of neurotransmitters such as dopamine, serotonin, and NE, directly promoting anxiety-like behaviors [460]

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Clip11262, however, was not able to infect Caco-2 cells, consistent with the fact that this non-pathogenic strain does not harbor the key virulence factors required for host infection ( Figure 1A , Figure 10 )