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In addition, when circulating L-carnitine concentration increases, as in the case of oral supplementation, renal reabsorption of L-carnitine may become saturated, resulting in increased urinary excretion of L-carnitine (5)

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Other groups have considered specific cell processes, such as anoikis, a form of apoptosis that has been implicated in cancer tumor progression and metastasis and that remains poorly understood in CaP

These ncRNA can impact mitochondria indirectly by affecting transcripts encoding for mitochondrial proteins in the cytoplasm

Posttranscriptional upregulation by microRNAs

References Abrahamsen RK, Lund AM, Rasmussen J (2023) Patients with primary carnitine deficiency treated with L-carnitine are alive and doing well-A 10-year follow-up in the Faroe Islands