bacterial and host-derived glutathione are required to activate prfa Allosteric GSH binding primes for DNA binding. (A B) Multiple regulatory check-points control prfA

Multiple regulatory check points control prfA expression and protein Download Scientific Diagram Listeria monocytogenes requires phosphotransferase systems to facilitate intracellular growth and virulence PMC Structural basis of promiscuous inhibition of Listeria virulence activator PrfA by oligopeptides: Cell Reports RCSB PDB 5LRS: The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione and a 30 bp operator PrfA box motif Streptococcus pyogenes Hijacks Host Glutathione for Growth and Innate Immune Evasion mBio Glutathione Provides a Source of Cysteine Essential for Intracellular Multiplication of Francisella tularensis PLOS Pathogens

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