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FIGURE 6 Discussion Diabetes, associated with insulin resistance and reduction in the level of insulin, mainly affects psychomotor activity, attention, learning, memory, cognition, mental flexibility in the brain ( Additionally, the treatment also prevented an increase in the level of APP and neuronal damage

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Statistical analyses The PK population consisted of all subjects who received lesinurad and had evaluable PK data, while the PD population consisted of all subjects who received lesinurad and had evaluable PD data