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What is truly promising is that there appears to be little to no toxicity in non-neoplastic cells

Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C et al (2015) Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits

Abstract Multiple neurodegenerative disorders, including Parkinsons disease (PD) and Alzheimers disease-associated dementia (ADAD), are linked with dopaminergic (DA) neuron death and a resulting reduction in dopamine levels in the brain

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Transport mechanism of NPTAs The translocation of drugs across the BBB to the brain mainly depends on passive diffusion and active transport mechanisms