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Although N-acetylcysteine (NAC) directly influences the pool of extracellular cystine and intracellular cysteine via a series of plasmatic redox reactions, in order to be effective, intracellular cysteine precursors must be designed to enter erythrocytes rapidly and use high activity enzymes within erythrocytes to liberate cysteine (Whillier et al., 2009

Among SCFAs, acetate and propionate primarily enter the liver via the portal vein, serving as precursors for fatty acid synthesis and gluconeogenesis, respectively

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Although no adverse pregnancy outcomes were reported in a study of Iranian women who took dehydrated garlic tablets (800 mg/day) for two months during the third trimester of pregnancy (153), the safety of garlic supplements in pregnancy has not been established

Natural killer (NK) cells are characterized by a reduced number and weakened cytotoxicity in kidney failure, which undermines immune surveillance and exacerbates systemic inflammation and immune imbalance (73, 74)