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This paradox makes biological sense when you consider the collateral vessel activation mechanism

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A study(13)was conducted on murine models with experimentally injured gastrocnemius muscle complex

Oct 2016;22(7):656-664

To evaluate the effect of Wnt/-catenin signaling on bleomycin-induced pulmonary fibrosis, we injected mice with salinomycin, a small-molecule Compound that specifically inhibits Wnt/-catenin, as previously described [30]