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Comparison between groups showed no difference in penetration at 072 hours, but at 96 hours penetration depth remained higher in the repeated group, suggesting that repeated manipulation may have contributed to slightly greater penetrability at later time points [2]

D.YongH.FranklinK

Main conclusions: GHK-Cu acts via 6 main mechanisms (described above) The endogenous decrease with age is documented in various populations Topical applications in dermatology are the best validated Antimicrobial effect , GHK-Cu also has a mild antibacterial profile The safety profile is excellent, no toxic doses were reached in animal studies Why it matters: This review became a reference source for the dermatological and cosmetic research community