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In the component of primary outcome, persistent 50% eGFR decline from baseline was significantly reduced in semaglutide group (HR 0.73, 95% CI 0.590.89)

In adolescents with type 1 diabetes, resistance exercise combined with glutamine supplementation led to a reduction in body fat mass, though it had no effect on lean body mass, glycated hemoglobin (HbA1c), or daily insulin dose [84]

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Regulation by Acetylation: GLS can be post-translationally modified through acetylation, affecting its activity

In summary, the mechanism of oxidative stress related to cardiac iron overload in -thalassemia patients involves the interplay of excess iron, increased ROS production, and the resultant cellular damage

Muthukumar K, Rajakumar S, Sarkar MN, Nachiappan V