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In the study by Corral-Jara et al., the researchers employed a multi-omics approach and discovered that EC metabolites derived from the gut microbiota, particularly -pentalactone-bound metabolites, exert significant anti-inflammatory effects by synergistically regulating mRNA, miRNA, lncRNA, and protein expression

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Neutral pH is generally safest for most peptides, which is convenient because bacteriostatic water has a near-neutral pH

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Gastroenterology 134 (4), 12151223

In fact, the major clinical trials showed the exact opposite effect