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The verification of clinical efficacy of metformin and the exploration of potential mechanisms have become the research hotspots in the field of cancer

Widely adopted guidelines define a moderate intake as 20 g/day for women and 30 g/day for men

Am J Physiol Lung Cell Mol Physiol 2001

[DOI] [PubMed] [Google Scholar] 100.Ghiselli G, Schaefer EJ, Gascon P, Breser HB

USA 116 , 1201912024 (2019)

293 In another study, multiplex immunofluorescence imaging was also performed in combination with single-cell sequencing to depict the microenvironment of primary breast cancer