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A study of infants with AP found significant improvements in physician-rated symptom scores, weight, and blood in the stool, as well as high parental satisfaction, with the use of an amino acid-based formula [25]

Strikingly, we found acinar cells were replaced by SOX2 + cells in the IR SLG (GFP + cells) similar to the nonIR control with the production of both SOX2 + GFP + and SOX2negative progeny (Fig 5D, white arrowheads indicate SOX2negative progeny), suggestive of the presence of a transitamplifying cell which is no longer SOX2 + but derived from a SOX2 + cell (i.e., lineagetraced)

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