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Zhang JR, Ouyang X, Hou C, Yang QF, Wu Y, Lu WJ, et al

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The use of mode of action information in risk assessment: Quantitative key events/dose-response framework for modeling the dose-response for key events

The dual activation of HACD44 and GSHNrf2 signaling pathways establishes a finely balanced biochemical microenvironment that supports cell proliferation, angiogenesis, and extracellular matrix maturation while preventing oxidative and inflammatory overactivation

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Data availability The datasets generated and analyzed during the current study are not publicly available, but are available from the corresponding author on reasonable request