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XPS measurements were carried out on the K-Alpha + X-ray Photoelectron Spectrometer System (Thermo Scientific), which features a Hemispheric 180 dual-focus analyzer with a 128-channel detector

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Future studies should conduct large-scale, multi-center randomized controlled trials to explore the pharmacokinetic characteristics, dose-response relationships, and potential side effects of silybin, thereby formulating scientifically sound medication guidelines

FIGURE 3 3.1.1 Curcumins epigenetic modulation: DNA methylation and wnt/ -catenin pathway regulation Curcumin exerts profound epigenetic regulatory effects in cancer by modulating DNA methylation and interfering with the Wnt/ -catenin signaling pathway, two mechanisms central to tumorigenesis and cell fate determination

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