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Description

78 out of 109 patients (72%) have marked improvement

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We observed that addition of electron-withdrawing substituents on the phenyl ring increased the electrophilicity of the chloroacetamide carbon and improved potency of inhibition (Supplementary Table 1)

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The vial should remain sealed when not in use, and all laboratory handling should follow appropriate sterile technique

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10.7554/eLife.25217 270 WuH.WangM.LiX.ShaoY

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