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Conversely, it decreased the activities of browning-related enzymes, such as polyphenoloxidase (PPO) and peroxidase (POD)

To determine whether ACE induced ferroptosis in tumor tissues, we measured the levels of the lipid peroxidation products MDA and Fe 2+ and found that ACE elevated the levels of MDA and increased the accumulation of Fe 2+ in mouse tumor tissues (Fig