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sphenanthera , has been shown to decrease APAP hepatotoxicity as well as to lead to features of liver regeneration by inhibiting NAPQI-initiated injury via the blockade of CYP activity, the down-regulation of p53/p21 and the up-regulation of other signaling pathways to facilitate hepatic tissue repair

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Autophagy is a self-degradative type of cell death accompanied by large-scale autophagic vacuolization of the cytoplasm, resulting in a vacuolated appearance in response to stressors, such as nutrient deprivation (130)

Positive and negative regulation of ferroptosis and its role in maintaining metabolic and redox homeostasis

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