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The single dose of 70 mg/kg has been used in models of acute toxicity and is below the oral LD for rats (75100 mg/kg), causing significant yet non-lethal organ damage [23, 24]

However, the underlying mechanisms and clinical efficacy remain unclear

At day 5, mice were euthanized by terminal anesthesia with ketamine and cardiac puncture, and subsequently the kidneys were harvested

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(1999) compared ipamorelin with GHRP-6 and GHRP-2 in a head-to-head study