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In 2 randomized, double-blind, placebo-controlled studies of adult chronic migraine sufferers, many study participants experienced a 50% reduction in headache days each month (8 to 9 days fewer headaches) through the use of BOTOX

2 Overview of DTP cells 2.1 The concept of DTP cells The fundamentals of DTP cells were first described in the 1940s to depict the phenomenon of antibiotic treatment-induced non-genetic tolerance in a small subset of bacteria (Russo et al., 2024)