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The medication works by enhancing insulin secretion in a glucose-dependent manner, suppressing glucagon release, and slowing gastric emptying, which collectively improves glycemic control and promotes weight loss

PMID 3081818

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They include abrocitinib (Cibinqo), ruxolitinib (Opzelura), and upadacitinib (Rinvoq)

Furthermore, the KEGG results revealed associations of these DEGs with pathways related to cholesterol metabolism, amino acid biosynthesis, and primary bile acid biosynthesis, among others (Figure 7D)