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Targeting the MIF pathway could therefore represent a promising therapeutic strategy, converting immunosuppressive MDSCs into pro-inflammatory, antitumor DC-like cells, and thereby reinvigorating antitumor immune responses in late-stage melanoma patients

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Dried down cell samples and media were stored at 80 C until further use

Archived from the original on 2 August 2014

In particular, a meta-analysis of observational studies suggested that lowering Hcy by 34 mol/L results in an approximately 3040% reduction in vascular disease [81]

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