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Structural lesions leading to vitamin B 12 deficiency include regional ileitis, ileal resections, malignancies, etc

Role of mitochondrial dysfunction, oxidative stress and autophagy in progression of Alzheimer's disease

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Theyre essential for obtaining energy, regulating hormones, forming red blood cells, breaking down blood sugar, metabolizing food, growing skin, hair, and nails, and promoting cell growth

A study of heat-exposed workers found that one 8-hour sweaty shift depletes: sodium 3,725 mg, potassium 514 mg, magnesium 18.4 mg, zinc 0.88 mg, vitamin C 15.7 mg, vitamin B1 0.23 mg, and vitamin B2 0.20 mg (PMC/NIH, 2016)

If you take high doses over a long period of time, niacin can damage the liver