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J Environ Manage 268:110610 Raven JA (2017) Chloride: essential micronutrient and multifunctional beneficial ion

Rostami, K

Cross-cancer comparisons reveal that although the SSP serves conserved functions in sustaining one-carbon unit supply and mediating therapeutic resistance across cancer types, the remarkable heterogeneity of its upstream regulatory mechanismsincluding Kras/FGFR3 mutations, MYC-mediated stemness maintenance, and m6A epigenetic modificationsdictates that therapeutic strategies must be precisely tailored