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106 Furthermore, when COX-2 was specifically overexpressed in hepatocytes, mice showed markedly attenuated obesity by enhancing AKT and AMPK-induced thermogenesis and energy expenditure

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While invasive methods such as DBS have shown remarkable efficacy in treating conditions such as Parkinsons disease, the associated surgical risks-including infection and bleeding-have driven the development of safer and non-invasive alternatives (Liu X