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Adhesions can also obliterate normal pelvic angles and induce abnormal uterine flexion, while nodularity and thickening of pelvic ligaments (uterosacral ligaments) with fibrotic reactions further disrupt pelvic anatomy ( Mechanically, these changes impair fertility through multiple pathways: extensive adhesions can occlude the tubal ostium and embed ovaries, blocking sperm passage and oocyte release

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Immunohistochemistry Immunohistochemistry was performed on paraffin-embedded EDTA decalcified mouse knee sections

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47 Additionally, cistanoside A showed protective effects against alcohol-induced hepatotoxicity in mice by improving hepatic function, reducing steatosis and inflammatory infiltration, enhancing free radical clearance, alleviating lipid peroxidation, and restoring mitochondrial energy metabolism