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Mechanistically, cancer cells capable of inducing cancer cachexia are secreting IL-6, which subsequently induces autophagy in differentiated muscle cells via IL-6 signaling and therefore might be relevant for the characteristic muscle and weight loss during cancer cachexia (276)

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The dendritic cells, which are the main guards, become paranoid

Phentermine increases norepinephrine release, raising systolic and diastolic pressure by 515 mmHg on average, while tirzepatide can independently cause tachycardia (elevated heart rate) in some patients, especially during dose escalation