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Metabolic transistor strategy for controlling electron transfer chain activity in Escherichia coli

The reactivity of RT probe towards GSH is obviously not questioned, and the use of this probe could be useful after verifying, possibly by HPLC, that in an experimental system the amount of GSH is at least one order of magnitude greater than that of Cys, both before and after any treatment aimed to change thiols levels

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How do glutathione and Nacetylcysteine (NAC) compare regarding indications, dosing, effectiveness, and safety for acetaminophen toxicity, mucolytic therapy, and general antioxidant supplementation?