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Kitt is the first-order rate constant for the disappearance of glucose (Kitt) during the 3 to 15 minutes period after intravenous insulin administration, and was taken as a measure of insulin sensitivity, and was calculated as follows: Kitt (%/min)=(0.693100)/t1/2, where t1/2 is the half-life calculated from the slope of the plasma glucose concentration

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Some individuals prefer lower concentration formulations to reduce injection site discomfort, while others prefer higher concentrations to minimize injection volume

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