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Description

The slowed gastric emptying combined with altered gut motility creates unpredictable effects on colonic transit

Clinical development of amino acid metabolism inhibitors faces challenges including identification of predictive biomarkers, management of toxicities related to effects on normal tissues, and emergence of resistance through metabolic rewiring

Drug mechanism meta-analysis Drug interaction data was examined using PubChem BioAssays results for the hits discovered in the Selleck Chemicals drug library screen described below 44,45,46