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A "tissue specific" promoter is only active in specific types of differentiated cells/tissues

[DOI] [PMC free article] [PubMed] [Google Scholar] Witticke D, Seidling HM, Klimm HD, Haefeli WE, 2012

Eur J Nutr., 54: 149

So it wasnt until like 20 years later in the early 2000s, this group of Ferguson and Blakely showed that this choline high affinity transporter is actually not on the neuron, its on the vesicle inside the neuron