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These are unstable molecules produced by UV radiation, air pollution, and even intense physical exercise

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For treatment, they offer drug targets, and understanding them aids in optimizing existing drugs and personalized therapy

As in the case of many chronic degenerative diseases, increased production of reactive oxygen species has been considered to play an important role, even in the pathogenesis of chronic fluoride toxicity

With 0.2 M H 2 O 2 , the 100-l supernatant that resulted was examined

Wang R, Chen C, Liu W, Zhou T, Xun P, He K, Chen P