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International journal of andrology

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In addition, multiple-alignment analyses demonstrated the presence of a considerable degree of conserved residues in main sites of both enzymes

Deficiency causes megaloblastic anaemia a form of anaemia that makes you feel exhausted and breathless

2008 Aug;128(8):1203-7

The complete absence of dimerization in C396S suggests that Cys396 may be involved in an inter-molecular disulfide bond that results in the formation of an oligomeric structure that combines GSAAT with other enzymes, factors or molecular chaperones involved in ALA formation, such as GluTR, GBP ( The purified UT recombinant GSAAT variants were not entirely reduced, and additional reducing power enhanced their enzyme activities