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Raninga PV, Trapani GD, Vuckovic S, Bhatia M, Tonissen KF

Copper(II) complexes of hybrid hydroxyquinoline-thiosemicarbazone ligands: GSK3 inhibition due to intracellular delivery of copper

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In our previous studies with both bulk (Gill et al, 2014) and scRNA-seq (Yuan et al, 2018), we observed that the mesenchymal phenotype was strongly associated with recurrent tumors and that the principal remaining glioma cell type with neural lineage resemblance was astrocyte-like