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however, no clinical trials of these types of mimics have been reported (Forman and Zhang 2021)

George, A

2010;125(5):e1249-1254

showed that TMAO production was dependent on the gut microbiota and that mice treated with antibiotics failed to provide the required gut microbiota for TMAO production ( ApoE / mice without changing circulating cholesterol levels (75)

To enhance sensitivity, specificity, and translational relevance, future research should incorporate multimodal biomarker strategiescombining imaging, fluid-based, and multi-omics analyses

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