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People Taking Certain Medications Long-term use of metformin (a common diabetes medication) and proton pump inhibitors (PPIs) like omeprazole can reduce B12 absorption over time

Do not rub the injection site afterward

Either way, it is often caused by a deficiency in vitamin B12

These methylation reactions also regulate gene expression during fetal development

Other Uses Compounded methylcobalamin injections and other forms of vitamin B12 injections like hydroxocobalamin and cyanocobalamin may also be prescribed for those with pernicious anemia, diabetes, neuropathy, heart disease, circadian rhythm sleep disorders, memory loss, depression, fatigue, AIDS, inflammatory bowel disease (IBD), Lyme disease, osteoporosis, tendonitis, psychiatric disorders, Alzheimers disease, liver and kidney disease, and asthma

Side effects such as nausea, constipation, acid reflux, stomach pain, vomiting, diarrhea, and injection site reactions are common