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The New England Journal of Medicine 376, (14) (Apr 6): 1311-1320

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Increasing evidence suggests that cell-mediated immunity has an important role in the pathogenesis of COPD, which is characterized by immune senescence leading to decreased resistance to infection, enhanced neutrophil and macrophage activation, T-cell infiltration, and aberrant B-cell activity, all of which combine to contribute to airway inflammation and lung injury in patients with COPD

Two recent studies used biosensor-based systems to extend productive lifetimes of heterologous vanillin- - glucoside and N -acetylglucosamine in Saccharomyces cerevisiae via selection of producing subpopulations [2122]

The slower rate of cell growth but higher migratory capacity of the less metabolically active OVCAR5 CBPR cells may suggest that these cells undergo migration at the expense of proliferation

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