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Change of inoculation route In addition to sequential immunization (mixed-vaccination), development of new vaccines (such as nanoparticle vaccine), and adjuvant improvement, changing the vaccination route is also a feasible measure to improve the protection and efficacy of existing COVID-19 vaccines

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Release of zonulin after bacterial exposure has been demonstrated in rat and human intestinal cell lines (IEC6 and Caco-2, respectively), and may facilitate the flushing out of microbes and toxins, participating in the innate immune response of the host to counter intestinal bacterial colonisation (117)

doi: 10.51470/bca.2024.24.2.2313 [DOI] [Google Scholar] 184

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