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Desensitisation: Prolonged use can lead to desensitization of the Leydig cells, reducing the effectiveness of HCG over time

Persistent fatigue and low energy are among the most common signs of a B12 or folate deficiency

However, our hypothesis is also consistent with the fact that for the first time we show that while vitamin B 12 deficiency was closely associated with metformin dose, consistent with previous studies [1, 8], it was not associated with plasma concentrations of metformin (Fig

Supports cell division, tissue repair, and rapid growth in clinical recovery and malnourished patients

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